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Associate Director, Medicinal Chemistry

This early stage biotech company provides an exciting opportunity in the Medicinal Chemistry world backed by funding. They focus on small molecule treatments for protein misfolding diseases and are growing fast!

Title: Associate Director of Medicinal Chemistry

Location: South San Francisco

Salary: Competitive based on experience

Must Have's:

-Ph.D in chemistry or related

-3-5 years of Medicinal Chemistry Experience (Protein-Protein interactions, SAR Relationships, PK, Novel Chemistry)

-Previous Management Experience (direct reports and CROs)

-Experience working with cross-functional groups (i.e. biologists, analytical chemists, PK)

Responsibility:

-Designing chemical analogs and scouting routes to access analogs

-Manage lead optimization of a series of allosteric small molecule ligands

-Direct a small team of medicinal chemists in the synthesis of analogues

~70% performing desk work including: chemical design at computer, chemical docking (w/computational biologists), and working with CROs (weekly reports and troubleshooting)

~30% in the lab working with: analytical chemists, PK biologists, and other cross functional teams

-working daily with the Associate director of R&D on the assays to characterize compounds, look at data, and interpret structure to advance compounds

-contribute to early discovery programs in the company pipeline

-coordinate additional work in-house and outsourced for solubility and PK

-Interface with IP team to write patents

Sthree US is acting as an Employment Agency in relation to this vacancy.